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Clients dealt with with flumazenil ought to be monitored for resedation, respiratory despair and also other residual benzodiazepine results for an acceptable period of time after procedure. The prescribers hould be aware of a danger of seizure in Affiliation with flumazenil cure, notably in extensive-term benzodiazepine people As well as in cyclic

Advise both individuals and caregivers in regards to the pitfalls of respiratory melancholy and sedation when diazepam is used with opioids. Suggest patients not to travel or run heavy machinery right until the consequences of concomitant use Together with the opioid are actually decided (see PRECAUTIONS: DRUG INTERACTIONS).Benzodiazepine treatment